教師簡介

  • 專任副教授、榮總兼任副研究員
  • 鍾明怡
  • Ming-yi Chung
  • 02-55683265
  • mychung@nycu.edu.tw
  • 榮總致德樓8樓R871
  • 專業領域
  • 分子遺傳學、細胞遺傳學、醫學遺傳學
  • 研究興趣
  • 利用分子遺傳學方法找尋並了解基因在致病機轉中所扮演的角色。
  • 研究方向

  • 1. 黃斑失養症之表現形與基因形間的關係。

    2. 家族性滲漏性玻璃體視網膜病變基因在NDP/wnt/β-catenin singaling pathway與 angiogenesis中的角色。

    3. 10q26基因多型性在老年性黃斑部病變的角色。

  • 執行計畫

  • 科技部 < MOST109-2314-B-010 -013 >家族性滲漏性玻璃體視網膜病變之分子遺傳學研究 4(2020/08/01-2021/07/31

  • 教授科目
  • 遺傳學概論
    基因體學
    醫學遺傳學
  • 獲獎
  • 1993
    Bacaner Research Award in Basic Medical Science, Minnesota Medical Foundation
  • 經歷
  • Nov, 2013-present
    臺北榮民總醫院醫學研究部
    兼任副研究員
  • Aug, 2006-present
    國立陽明交通大學
    生命科學系暨基因體科學研究所
    副教授
  • Aug, 2005-Oct, 2013
    臺北榮民總醫院教學研究部
    兼任副研究員
  • Aug, 2005-Jul, 2006
    國立陽明大學遺傳學研究所
    副教授
  • Aug, 2002-Jul, 2005
    國立陽明大學遺傳學研究所
    兼任副教授
  • May, 1997-Aug, 2005
    臺北榮民總醫院教學研究部
    副研究員
  • Oct, 1994-May, 1997
    臺北榮民總醫院
    病理檢驗部臨床細胞遺傳實驗室
    約聘技術師
  • 1994
    美國明尼蘇達大學
    分子遺傳臨床細胞遺傳
    博士後研究
  • 學歷
  • 1993
    美國明尼蘇達大學 (University of Minnesota, Minneapolis)
    病理生物 (Pathobiology)　博士
  • 1990
    美國明尼蘇達大學
    臨床實驗科學 (Clinical Laboratory Science)　碩士
  • 1987
    國立臺灣大學
    醫事技術學系　學士

代表著作

  • Chung, M.Y.*, Chen SJ, Jiang YJ (2021) Phenotype Variability in the Patients of Familial Exudative Vitreoretinopathy: the RCBTB1 case. Curr Eye Res 46 (12):1931. doi:10.1080/02713683.2021.1924383
  • Chen PC, Huang HY,Chung, M.Y., Pan CC (2021) Ossifying low grade endometrial stromal sarcoma with PHF1-BRD8 fusion. Cancer Genet 256-257:81-85. doi:10.1016/j.cancergen.2021.04.00
  • Wu CC, Hsieh MY, Lee CK, Chuang SY, Chung, M.Y.*, Lin CC (2019) Dimethylarginine Dimethylaminohydrolase 1 Polymorphisms and Venous Intimal Hyperplasia in Hemodialysis Patients. American journal of nephrology 50 (6):454-464. doi:10.1159/000503949
  • Liao KW, Chang CH, Tsai MS, Chien LC, Chung, M.Y., Mao IF, Tsai YA, Chen ML (2018) Associations between urinary total arsenic levels, fetal development, and neonatal birth outcomes: A cohort study in Taiwan. The Science of the total environment 612:1373-1379. doi:10.1016/j.scitotenv.2017.08.312
  • Chen S-P, Fuh J-L, Chung, M.Y.1, Lin Y-C, Liao Y-C, Wang Y-F, Hsu C-L, Yang U-C, Lin M-W, Chiou J-J, Wang P-J, Chen P-K, Fan P-C, Wu J-Y, Chen Y-T, Kao L-S, Fann CS-J, Wang S-J (2018) Genome-wide association study identifies novel susceptibility loci for migraine in Han Chinese resided in Taiwan. Cephalalgia : an international journal of headache 38 (3):466-475. doi:doi:10.1177/0333102417695105
  • Chang CH, Yu CJ, Du JC, Chiou HC, Chen HC, Yang W,Chung, M.Y., Chen YS, Hwang B, Mao IF, Chen ML (2018) The interactions among organophosphate pesticide exposure, oxidative stress, and genetic polymorphisms of dopamine receptor D4 increase the risk of attention deficit/hyperactivity disorder in children. Environmental research 160:339-346. doi:10.1016/j.envres.2017.10.011
  • Yu CJ, Du JC, Chiou HC, Yang SH, Liao KW, Yang W, Chung, M.Y., Chien LC, Hwang B, Chen ML (2016) Attention Deficit/Hyperactivity Disorder and Urinary Nonylphenol Levels: A Case-Control Study in Taiwanese Children. PloS one 11 (2):e0149558. doi:10.1371/journal.pone.0149558
  • Yu CJ, Du JC, Chiou HC, Feng CC, Chung, M.Y., Yang W, Chen YS, Chien LC, Hwang B, Chen ML (2016) Sugar-Sweetened Beverage Consumption Is Adversely Associated with Childhood Attention Deficit/Hyperactivity Disorder. International journal of environmental research and public health 13 (7):E678. doi:10.3390/ijerph13070678
  • Yu CJ, Du JC, Chiou HC, Chung, M.Y., Yang W, Chen YS, Fuh MR, Chien LC, Hwang B, Chen ML (2016) Increased risk of attention-deficit/hyperactivity disorder associated with exposure to organophosphate pesticide in Taiwanese children. Andrology 4 (4):695-705. doi:10.1111/andr.12183
  • Wu JH, Liu JH, Ko YC, Wang CT, Chung YC, Chu KC, Liu TT, Chao HM, Jiang YJ, Chen SJ, Chung, M.Y.* (2016) Haploinsufficiency of RCBTB1 is associated with Coats disease and familial exudative vitreoretinopathy. Human molecular genetics 25 (8):1637-1647. doi:10.1093/hmg/ddw041
  • Lee KH, Tsai WJ, Chen YW, Yang WC, Lee CY, Ou SM, Chen YT, Chien CC, Lee PC, Chung, M.Y.*, Lin CC (2016) Genotype polymorphisms of genes regulating nitric oxide synthesis determine long-term arteriovenous fistula patency in male hemodialysis patients. Renal failure 38 (2):228-237. doi:10.3109/0886022X.2015.1120096
  • Fuh JL, Chung, M.Y.1, Yao SC, Chen PK, Liao YC, Hsu CL, Wang PJ, Wang YF, Chen SP, Fann CS, Kao LS, Wang SJ (2016) Susceptible genes of restless legs syndrome in migraine. Cephalalgia : an international journal of headache 36 (11):1028-1037. doi:10.1177/0333102415620907
  • Chen YW, Wu YT, Lin JS, Yang WC, Hsu YH, Lee KH, Ou SM, Chen YT, Shih CJ, Lee PC, Chan CH, Chung, M.Y.*, Lin CC (2016) Association of Genetic Polymorphisms of Renin-Angiotensin-Aldosterone System-Related Genes with Arterio-Venous Fistula Malfunction in Hemodialysis Patients. International journal of molecular sciences 17 (6). doi:10.3390/ijms17060833
  • Tseng SH, Cheng CY, Huang MZ, Chung, M.Y.*, Su TS (2013) Modulation of formation of the 3'-end of the human argininosuccinate synthetase mRNA by GT-repeat polymorphism. International journal of biochemistry and molecular biology 4 (4):179-190
  • Lin CC, Chung, M.Y., Yang WC, Lin SJ, Lee PC (2013) Length polymorphisms of heme oxygenase-1 determine the effect of far-infrared therapy on the function of arteriovenous fistula in hemodialysis patients: a novel physicogenomic study. Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 28 (5):1284-1293. doi:10.1093/ndt/gfs608.
  • Chang CF, Lu TM, Yang WC, Lin SJ, Lin CC, Chung, M.Y.* (2013) Gene polymorphisms of interleukin-10 and tumor necrosis factor-alpha are associated with contrast-induced nephropathy. American journal of nephrology 37 (2):110-117. doi:10.1159/000346528
  • Lin CS, Wang LS, Chang SC, Chou TY, Hsu WH, Liu CS, Lee MH, Chung, M.Y., Wei YH (2012) Associated microsatellite alterations in mitochondrial DNA and in TP53 in thoracic esophageal squamous cell carcinoma. Oncology reports 28 (1):69-76. doi:10.3892/or.2012.1761
  • Lee YC, Durr A, Majczenko K, Huang YH, Liu YC, Lien CC, Tsai PC, Ichikawa Y, Goto J, Monin ML, Li JZ, Chung, M.Y., Mundwiller E, Shakkottai V, Liu TT, Tesson C, Lu YC, Brice A, Tsuji S, Burmeister M, Stevanin G, Soong BW (2012) Mutations in KCND3 cause spinocerebellar ataxia type 22. Ann Neurol 72 (6):859-869. doi:10.1002/ana.23701
  • Hsu CP, Lin SJ, Chung, M.Y., Lu TM (2012) Asymmetric dimethylarginine predicts clinical outcomes in ischemic chronic heart failure. Atherosclerosis 225 (2):504-510. doi:10.1016/j.atherosclerosis.2012.09.040
  • Chiang CH, Lin MW, Chung, M.Y., Yang UC (2012) The association between the IL-4, ADRbeta2 and ADAM 33 gene polymorphisms and asthma in the Taiwanese population. Journal of the Chinese Medical Association : JCMA 75 (12):635-643. doi:10.1016/j.jcma.2012.08.012

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